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Isaac Hitchock was born 1724 in Baltimore, MD. His siblings were Ann Hitchock (1722-1792), Anne Hitchock (1717-1773), Elizabeth Hitchock (1720-?), Josiah Hitchock (1726-?), Jemima Hitchock (1726-?), William Hitchock (1728-?), Presiotia Hitchock (1720-1750), Asahel Hitchock (1719-1791), Nickles Hitchock (1730-?).