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Isaac Whitaker was born 3 MAR 1798 in Oddville, Harrison, Kentucky. His siblings were Susanna Whitaker (1778-?), Josiah J. Whitaker (1779-1850), Amelia Whitaker (1781-?), Nancy Ann Whitaker (1784-?), Margaret Whitaker (1791-?), Peter Whitaker (1793-?), Mary Whitaker (1796-?), Simeon Whitaker (1801-?).